Saturday, 21 April 2012

Anodesyn Suppositories





1. Name Of The Medicinal Product



Anodesyn Suppositories



Tesco Haemorrhoid Relief Suppositories



Care Haemorrhoid Relief Suppositories



Sainsburys Haemorrhoid Relief Suppositories



Boots Haemorrhoid Relief Suppositories


2. Qualitative And Quantitative Composition








Allantoin




10.25mg




Lidocaine Hydrochloride




10.25mg



For excipients, see 6.1



3. Pharmaceutical Form



Suppositories



White or nearly white suppositories.



4. Clinical Particulars



4.1 Therapeutic Indications



For the symptomatic relief of pain and irritation associated with haemorrhoids.



4.2 Posology And Method Of Administration



Route of administration: For rectal administration.



Adults and the elderly.



If necessary empty the bowels before using the suppository. Remove the protective film and insert the suppository as deep as possible into the rectum. One suppository should be inserted night and morning after each bowel movement. Do not use for more than 7 days unless advised by your doctor.



Children.



Not recommended for children.



4.3 Contraindications



Hypersensitivity to any of the ingredients, especially lidocaine.



4.4 Special Warnings And Precautions For Use



Anodesyn Suppositories/Tesco Haemorrhoid Relief Suppositories / Boots Haemorrhoid Suppositories / Care Haemorrhoid Relief Suppositories/Sainsburys Haemorrhoid Relief Suppositories are intended for use for short periods and should not be used for longer than 7 days without medical advice. Patients should be instructed to seek medical advice if they experience persistent pain or bleeding from the anus, especially where associated with a change in bowel habit, if the stomach is distended or if they are losing weight.



The label will state:



Keep all medicines out of the reach and sight of children.



If symptoms persist for more than 7 days consult your doctor.



4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction



No clinically significant drug interactions known.



4.6 Pregnancy And Lactation



The safety of Anodesyn Suppositories/Tesco Haemorrhoid Relief Suppositories/Boots Haemorrhoid Suppositories /Care Haemorrhoid Relief Suppositories/Sainsburys Haemorrhoid Relief Suppositories in pregnancy and lactation has not been established, but it is thought unlikely to constitute a hazard, though caution should be exercised during the first trimester.



Lidocaine crosses the placenta and is distributed into breast milk..



4.7 Effects On Ability To Drive And Use Machines



No or negligible influence.



4.8 Undesirable Effects



Hypersensitivity to any of the ingredients, particularly lidocaine. Occasionally may cause diarrhoea.



4.9 Overdose



Accidental ingestion may result in anaesthesia of the upper respiratory tract, nausea, vomiting and abdominal discomfort. Ingestion of very large quantities could result in CNS and cardiovascular toxicity.



Treatment should be symptomatic and supportive.



5. Pharmacological Properties



5.1 Pharmacodynamic Properties



C05A D0l - Products containing local anaesthetics



Lidocaine has a local anaesthetic action, relieving pain and discomfort in the affected areas. Allantoin is claimed to promote healing.



5.2 Pharmacokinetic Properties



Not applicable



5.3 Preclinical Safety Data



There are no pre-clinical data of relevance to the prescriber which are additional to that already included in other sections of the SPC.



6. Pharmaceutical Particulars



6.1 List Of Excipients



Colloidal Anhydrous Silica



Witepsol W35



Purified Water



6.2 Incompatibilities



Not applicable



6.3 Shelf Life



Three years.



6.4 Special Precautions For Storage



Store at or below 25°C.



6.5 Nature And Contents Of Container



A white polythene lined, unplasticised PVC moulded strip, heat sealed and placed into a printed carton, containing 12 or 24 suppositories.



6.6 Special Precautions For Disposal And Other Handling



None stated.



7. Marketing Authorisation Holder



Thornton & Ross Limited



Linthwaite



Huddersfield



West Yorkshire



HD7 5QH



United Kingdom



8. Marketing Authorisation Number(S)



PL 00240/0071



9. Date Of First Authorisation/Renewal Of The Authorisation



6th September 2002



10. Date Of Revision Of The Text



14/04/2011




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